Duchenne Muscular Dystrophy Vs Muscular Dystrophy

Duchenne Muscular Dystrophy (DMD) is a severe type of muscular dystrophy caused by mutations in the dystrophin gene, which is essential for maintaining the structural integrity of muscle fibers. This X-linked genetic disorder primarily affects males and is characterized by progressive muscle weakness and degeneration, typically beginning in early childhood. Symptoms often include difficulty in walking, frequent falls, and muscle wasting, leading to loss of mobility by the teenage years. As the disease progresses, it can also affect the heart and respiratory muscles, significantly impacting the individual's overall health and life expectancy.

Muscular Dystrophy (MD) is a broad term that encompasses a group of inherited genetic disorders characterized by progressive muscle weakness and degeneration due to defects in the genes responsible for muscle structure and function. There are several types of muscular dystrophy, each with varying patterns of inheritance, onset, and severity. Common forms include Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, and Myotonic Dystrophy, among others. While MD primarily affects voluntary muscles involved in movement, it can also impact involuntary muscles, leading to complications such as heart disease and respiratory issues. The progression of muscular dystrophy varies widely, with some individuals maintaining mobility into adulthood while others may experience significant disability at a young age.