Necrosis Vs Infarction

Necrosis is a pathological process characterized by the premature death of cells in living tissue due to factors such as injury, infection, or lack of blood supply. It results from the failure of cellular metabolism and is often accompanied by inflammation. The affected tissue undergoes a series of changes, including cell swelling, rupture of cell membranes, and the release of cellular contents into the surrounding area, which can lead to further tissue damage and an inflammatory response.

Infarction refers to the localized death of tissue due to inadequate blood supply, typically resulting from an obstruction in the blood vessels, such as a clot or embolism. This interruption of blood flow deprives the affected area of oxygen and nutrients, leading to tissue damage and necrosis. Infarction can occur in various organs, with myocardial infarction (heart attack) and cerebral infarction (stroke) being among the most clinically significant forms, highlighting the importance of timely medical intervention.